Star striker Robin Van Persie is set to miss this final fixture due to suspension after picking up tow yellow cards.
They could also be without defender Bruno Martins Indi, who suffered concussion against Australia.
Chile head coach Jorge Sampaoli might leave out midfielders Arturo Vidal and Charles Aranguiz.
The pair have both been nursing injuries and each have a yellow card to their name, so another booking would rule them out of the next match.
DATE: June 23, 2014
TIME: 17 :00 BST
VENUE: Arena de Sao Paulo, Sao Paulo
POSSIBLE LINE UP:
NETHERLAND: Cillessen; de Vrij, Vlaar, Martins Indi; Janmaat, Blind; de Jong; de Guzman, Sneijder, Robben; Lens.
CHILE: Bravo; Isla, Medel, Jara, Mena; Vidal, Aranguiz, Diaz, Silva; Sanchez, Vargas.